Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457924 | 1.00 | EPHX1 (0.40) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL2381945 | 1.00 | EPHX1 (0.40) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL10105672 | 0.89 | TSHR (0.36) | TSHR | |
| SCHEMBL29815171 | 0.88 | EPHX1 (0.42) | EPHX1CA12CA1CA2MMP2 | |
| Hydrochloric Acid SCHEMBL23649914 | 0.86 | EPHX1 (0.41) | EPHX1CA12CA1CA2MMP2 | |
| Hydrochloric Acid SCHEMBL23649912 | 0.86 | EPHX1 (0.41) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL9608683 | 0.85 | EPHX1 (0.39) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL18353906 | 0.81 | MEN1 (0.33) | EPHX1ALDH1A1TSHR | |
| SCHEMBL28817735 | 0.80 | EPHX1 (0.35) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL11170830 | 0.80 | TSHR (0.50) | EPHX1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194144-A | Prodrugs of phosphoramide nucleotide analogs and pharmaceutical uses thereof | 吉利德科学公司 | 2023-05-30 | — | — | CN | disclosed |