Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 12/20 | 0.47 |
| ▸ | HTR2C | P28335 | 12/20 | 0.47 |
| ▸ | HTR2A | P28223 | 8/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30458591 | 0.94 | HTR2B (0.47) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30459137 | 0.85 | HTR2B (0.47) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30459956 | 0.85 | HTR2B (0.50) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30458630 | 0.83 | HTR2B (0.43) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30458409 | 0.83 | HTR2B (0.44) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL31076554 | 0.83 | HTR2B (0.47) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30458971 | 0.83 | HTR2B (0.44) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30459712 | 0.81 | HTR2B (0.43) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL30352321 | 0.81 | PARP1 (0.47) | HTR2BHTR2CHTR2APARP1HTR3E | |
| SCHEMBL25419396 | 0.80 | HTR2C (0.39) | HTR2BHTR2CHTR2APARP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |