Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 10/20 | 0.42 |
| ▸ | VEGFA | P15692 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30458627 | 0.87 | CRBN (0.49) | CRBNIKZF3 | |
| SCHEMBL25647385 | 0.83 | CRBN (0.58) | CRBNIKZF3 | |
| SCHEMBL30458815 | 0.83 | PARP1 (0.47) | CRBNIKZF3VEGFAEGLN1PARP1 | |
| SCHEMBL30459355 | 0.80 | CRBN (0.53) | CRBNIKZF3 | |
| SCHEMBL25647388 | 0.80 | CRBN (0.54) | CRBNIKZF3 | |
| SCHEMBL30458263 | 0.80 | CRBN (0.55) | CRBNIKZF3 | |
| SCHEMBL25234529 | 0.79 | VEGFA (0.39) | CRBNIKZF3VEGFAEGLN1 | |
| SCHEMBL30458385 | 0.79 | CRBN (0.54) | CRBNIKZF3 | |
| SCHEMBL30459375 | 0.79 | CRBN (0.54) | CRBNIKZF3 | |
| SCHEMBL30458491 | 0.78 | CRBN (0.49) | CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |