Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | NPY1R | P25929 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314882 | 0.97 | ESR1 (0.64) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL27259212 | 0.92 | ESR1 (0.59) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL23660874 | 0.92 | ESR1 (0.59) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL26184181 | 0.92 | ESR1 (0.59) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL25079599 | 0.89 | ESR1 (0.62) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL13875376 | 0.88 | ESR1 (0.58) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL26645551 | 0.88 | ESR1 (0.56) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL25479881 | 0.88 | ESR1 (0.59) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL31571975 | 0.87 | ESR1 (0.55) | ESR1ESR2MLNRNR1I2NR3C1 | |
| SCHEMBL30952384 | 0.87 | ESR1 (0.55) | ESR1ESR2MLNRNR1I2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |