Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.55 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.41 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30458500 | 0.96 | CRBN (0.55) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL30458935 | 0.83 | CRBN (0.51) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL31077158 | 0.83 | CRBN (0.61) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL25646992 | 0.83 | CRBN (0.61) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL26095517 | 0.81 | CRBN (0.59) | CRBNDDB1IKZF3 | |
| SCHEMBL30351516 | 0.81 | CRBN (0.59) | CRBNDDB1IKZF3 | |
| SCHEMBL30459790 | 0.81 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL30458550 | 0.81 | CRBN (0.53) | CRBNDDB1IKZF3 | |
| SCHEMBL25276056 | 0.80 | CRBN (0.64) | CRBNDDB1IKZF3 | |
| SCHEMBL30458583 | 0.80 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |