Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.79 |
| ▸ | EZH1 | Q92800 | 9/20 | 0.73 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.65 |
| ▸ | EED | O75530 | 2/20 | 0.65 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.65 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.65 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.65 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.65 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584139 | 1.00 | EZH2 (0.79) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL12684416 | 0.88 | EZH2 (1.00) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL30122893 | 0.88 | EZH2 (1.00) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL12180699 | 0.88 | EZH2 (0.76) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL12180842 | 0.88 | EZH2 (0.81) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2588701 | 0.88 | EZH2 (1.00) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2594244 | 0.85 | EZH2 (0.84) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL12180714 | 0.85 | EZH2 (0.85) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2592809 | 0.85 | EZH2 (0.83) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2588359 | 0.85 | EZH2 (0.82) | EZH2EZH1PRMT3EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |