Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.80 |
| ▸ | INSR | P06213 | 10/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.71 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.71 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.71 |
| ▸ | ROS1 | P08922 | 3/20 | 0.71 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.71 |
| ▸ | PLK4 | O00444 | 2/20 | 0.71 |
| ▸ | JAK2 | O60674 | 2/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.71 |
| ▸ | ABL1 | P00519 | 2/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.71 |
| ▸ | LCK | P06239 | 2/20 | 0.71 |
| ▸ | FES | P07332 | 2/20 | 0.71 |
| ▸ | LYN | P07948 | 2/20 | 0.71 |
| ▸ | RET | P07949 | 2/20 | 0.71 |
| ▸ | IGF1R | P08069 | 2/20 | 0.71 |
| ▸ | MET | P08581 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459769 | 0.93 | ALK (0.89) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL30459649 | 0.88 | ALK (0.75) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL30924829 | 0.87 | ALK (0.76) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL30761548 | 0.86 | ALK (0.87) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL28619135 | 0.86 | ALK (0.87) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL14780839 | 0.85 | ALK (0.73) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL21478104 | 0.85 | ALK (0.87) | ALKINSRFGFR2FGFR4FGFR3 | |
| SCHEMBL28619123 | 0.85 | ALK (0.87) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL31100375 | 0.84 | ALK (0.62) | ALKINSRKCNH2FGFR2FGFR4 | |
| SCHEMBL31100798 | 0.84 | ALK (0.59) | ALKINSRKCNH2FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745138-A1 | THIO-GLUTARIMIDO ISOINDOLINONE DERIVATIVE, BIFUNCTIONAL PROTEIN DEGRADER CONTAINING SAME, AND USES THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |
| EP-4446324-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2024-10-16 | — | — | EP | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |