Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | TEK | Q02763 | 2/20 | 0.63 |
| ▸ | TGM2 | P21980 | 7/20 | 0.63 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TGM1 | P22735 | 1/20 | 0.54 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767000 | 0.84 | KMT2A (0.69) | KMT2AEPHX2TEKEPHB4MAPT | |
| SCHEMBL18812119 | 0.83 | MAPT (0.61) | KMT2AEPHX2TEKEPHB4MAPT | |
| SCHEMBL29277130 | 0.81 | EGFR (0.65) | EPHX2TEKTGM2EPHB4MAPT | |
| SCHEMBL30684939 | 0.81 | EGFR (0.65) | EPHX2TEKTGM2EPHB4MAPT | |
| SCHEMBL9285859 | 0.81 | KMT2A (0.64) | KMT2AEPHX2MAPTTRPV1CA12 | |
| SCHEMBL2090980 | 0.81 | KMT2A (0.64) | KMT2AEPHX2MAPTTRPV1LMNA | |
| SCHEMBL8858788 | 0.81 | KMT2A (0.73) | KMT2AEPHX2MAPTTRPV1LMNA | |
| SCHEMBL9265165 | 0.81 | KMT2A (0.64) | KMT2AEPHX2MAPTTRPV1CA12 | |
| SCHEMBL8858784 | 0.81 | KMT2A (0.73) | KMT2AEPHX2MAPTTRPV1LMNA | |
| SCHEMBL11555827 | 0.80 | EPHX2 (1.00) | KMT2AEPHX2MAPTTRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069700-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111170999-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |