Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23065821 | 1.00 | EGFR (0.88) | EGFR | |
| SCHEMBL22821945 | 0.94 | EGFR (0.91) | EGFR | |
| SCHEMBL30459687 | 0.94 | EGFR (0.81) | EGFR | |
| SCHEMBL25227377 | 0.94 | EGFR (0.81) | EGFR | |
| SCHEMBL22025688 | 0.93 | EGFR (1.00) | EGFR | |
| SCHEMBL30381642 | 0.93 | EGFR (1.00) | EGFR | |
| SCHEMBL30579737 | 0.92 | EGFR (0.88) | EGFR | |
| SCHEMBL25340594 | 0.92 | EGFR (0.88) | EGFR | |
| SCHEMBL24207959 | 0.91 | EGFR (0.75) | EGFR | |
| SCHEMBL22821733 | 0.91 | EGFR (0.95) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |