Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.71 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.66 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 4/20 | 0.65 |
| ▸ | BACE1 | P56817 | 4/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285074 | 0.90 | APP (0.86) | APPSLC5A1SLC5A2ABCG2GSK3B | |
| SCHEMBL20169867 | 0.90 | APP (0.86) | APPSLC5A1SLC5A2ABCG2GSK3B | |
| SCHEMBL25196413 | 0.90 | APP (0.86) | APPSLC5A1SLC5A2ABCG2GSK3B | |
| SCHEMBL27723382 | 0.89 | APP (0.74) | APPABCG2GSK3BBACE1MAOB | |
| SCHEMBL27723380 | 0.89 | APP (0.74) | APPABCG2GSK3BBACE1MAOB | |
| SCHEMBL2970084 | 0.87 | APP (0.66) | APPABCG2GSK3BMEN1MAPT | |
| SCHEMBL7751094 | 0.87 | HDAC8 (0.62) | APPSLC5A1SLC5A2ABCG2MAOB | |
| SCHEMBL7751091 | 0.87 | HDAC8 (0.62) | APPSLC5A1SLC5A2ABCG2MAOB | |
| SCHEMBL25199799 | 0.86 | APP (0.80) | APPSLC5A1SLC5A2ABCG2GSK3B | |
| SCHEMBL25191246 | 0.86 | APP (0.80) | APPSLC5A1SLC5A2ABCG2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253226-B1 | Use of hydroxyflavone derivatives for modifying taste | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | APP 4361/4885SLC5A1 34/4885SLC5A2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.