Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687957 | 1.00 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25233033 | 0.99 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25276179 | 0.99 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25241032 | 0.95 | SLCO1B1 (0.47) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25285536 | 0.95 | SLCO1B1 (0.47) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30460057 | 0.91 | SLCO1B1 (0.47) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25231353 | 0.91 | SLCO1B1 (0.47) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30460076 | 0.88 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25278849 | 0.88 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25691468 | 0.88 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640117-A | Triazole LPAR1 antagonists and uses thereof | 武汉人福创新药物研发中心有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |