Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.44 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350597 | 1.00 | HDAC6 (0.44) | HDAC6KDM1AHDAC1KDM1BRET | |
| SCHEMBL25349877 | 0.90 | HDAC6 (0.44) | HDAC6KDM1AKDM1B | |
| SCHEMBL30460314 | 0.90 | HDAC6 (0.44) | HDAC6KDM1AKDM1B | |
| SCHEMBL30460211 | 0.88 | HDAC6 (0.47) | HDAC6KDM1AHDAC1RET | |
| SCHEMBL25351650 | 0.88 | HDAC6 (0.47) | HDAC6KDM1AHDAC1RET | |
| SCHEMBL25349968 | 0.88 | HDAC1 (0.43) | HDAC6KDM1AHDAC1KDM1B | |
| SCHEMBL30460250 | 0.88 | HDAC1 (0.43) | HDAC6KDM1AHDAC1KDM1B | |
| SCHEMBL30460187 | 0.87 | HDAC6 (0.48) | HDAC6HDAC1 | |
| SCHEMBL25350692 | 0.87 | HDAC6 (0.48) | HDAC6HDAC1 | |
| SCHEMBL25349552 | 0.85 | HDAC6 (0.46) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |