Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350328 | 0.86 | HDAC6 (0.47) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL24216706 | 0.86 | HDAC6 (0.51) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL30410124 | 0.86 | HDAC6 (0.51) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL24216316 | 0.84 | HDAC1 (0.47) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL24216393 | 0.81 | HDAC6 (0.51) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL31535166 | 0.81 | HDAC6 (0.51) | HDAC6HDAC1ALKCDC7EPHB4 | |
| SCHEMBL25351764 | 0.81 | HDAC6 (0.61) | HDAC6HDAC1CDC7EPHB4KDR | |
| SCHEMBL25352540 | 0.79 | HDAC6 (0.52) | HDAC6HDAC1 | |
| SCHEMBL25993121 | 0.78 | HDAC6 (0.48) | HDAC6HDAC1EPHB4KDRTEK | |
| SCHEMBL25217353 | 0.78 | HDAC6 (0.52) | HDAC6CDC7EPHB4KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |