Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417933 | 0.81 | NOTUM (0.48) | NOTUMTSHRRAB9ANPC1 | |
| SCHEMBL12901577 | 0.78 | NOTUM (0.46) | NOTUMTSHRMAPTALDH1A1HPGD | |
| SCHEMBL13778386 | 0.78 | NOTUM (0.56) | NOTUMTSHRRAB9AMAPTNPC1 | |
| SCHEMBL4171974 | 0.78 | TSHR (0.51) | NOTUMTSHRMAPTALDH1A1HPGD | |
| SCHEMBL23451501 | 0.74 | NOTUM (1.00) | NOTUMALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL12923857 | 0.74 | NOTUM (0.62) | NOTUMTSHRMAPTALDH1A1HPGD | |
| SCHEMBL31417991 | 0.74 | NOTUM (0.42) | NOTUMTSHRMAPTALDH1A1HPGD | |
| SCHEMBL31417844 | 0.73 | NOTUM (0.44) | NOTUMRAB9ANPC1 | |
| SCHEMBL13466849 | 0.73 | NOTUM (0.57) | NOTUMTSHRRAB9AMAPTNPC1 | |
| SCHEMBL14814390 | 0.72 | NOTUM (1.00) | NOTUMTSHRRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |