Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25275333 | 1.00 | KMT2A (0.44) | KMT2AMEN1HASPINPOLBGAA | |
| SCHEMBL15507768 | 0.84 | HASPIN (0.42) | KMT2AMEN1HASPINPOLBGAA | |
| SCHEMBL27034848 | 0.84 | HASPIN (0.42) | KMT2AMEN1HASPINPOLBGAA | |
| SCHEMBL26341310 | 0.80 | HASPIN (0.40) | KMT2AMEN1HASPINGAAHTT | |
| SCHEMBL21133651 | 0.80 | HASPIN (0.40) | KMT2AMEN1HASPINGAAHTT | |
| SCHEMBL25230721 | 0.80 | HASPIN (0.40) | KMT2AMEN1HASPINPOLBHTT | |
| SCHEMBL30460844 | 0.80 | HASPIN (0.40) | KMT2AMEN1HASPINPOLBHTT | |
| SCHEMBL21402713 | 0.80 | HASPIN (0.40) | KMT2AMEN1HASPINGAAHTT | |
| SCHEMBL25276973 | 0.79 | HASPIN (0.39) | KMT2AMEN1HASPINGAAHTT | |
| SCHEMBL25230364 | 0.79 | HASPIN (0.39) | KMT2AMEN1HASPINGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354957-A | CDK9 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |