⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629112 | 0.81 | — | — | |
| SCHEMBL23674407 | 0.73 | — | — | |
| SCHEMBL20400098 | 0.73 | — | — | |
| SCHEMBL7511961 | 0.70 | — | — | |
| SCHEMBL30043083 | 0.69 | — | — | |
| SCHEMBL2361417 | 0.65 | — | — | |
| SCHEMBL9860256 | 0.57 | — | — | |
| SCHEMBL1846183 | 0.57 | — | — | |
| SCHEMBL23674509 | 0.56 | — | — | |
| SCHEMBL7638133 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617802-B2 | Sulfonimidamide compounds as NLRP3 modulators | GENENTECH, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| US-20230159555-A1 | SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS | GENENTECH, INC. (US) | 2023-05-25 | — | — | US | disclosed |