Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463271 | 1.00 | HSD17B10 (0.38) | HSD17B10GAADRD2SLC6A4ALDH1A1 | |
| SCHEMBL24463552 | 0.94 | GAA (0.43) | HSD17B10GAADRD2SLC6A4ALDH1A1 | |
| SCHEMBL24463663 | 0.86 | LRRK2 (0.37) | HSD17B10GAADRD2SLC6A4DDB1 | |
| SCHEMBL24463541 | 0.80 | CYP17A1 (0.41) | HSD17B10GAADRD2SLC6A4ALDH1A1 | |
| SCHEMBL24463284 | 0.80 | IDO1 (0.42) | HSD17B10GAADRD2SLC6A4ALDH1A1 | |
| SCHEMBL30490091 | 0.78 | DDB1 (0.33) | DDB1CRBNIKZF3KMT2ATHRB | |
| SCHEMBL30390291 | 0.78 | DDB1 (0.33) | DDB1CRBNIKZF3KMT2ATHRB | |
| SCHEMBL24463356 | 0.78 | DDB1 (0.33) | DDB1CRBNIKZF3KMT2ATHRB | |
| SCHEMBL24463571 | 0.78 | FGFR1 (0.38) | HSD17B10GAADRD2SLC6A4ALDH1A1 | |
| SCHEMBL15748917 | 0.75 | EGFR (0.40) | HSD17B10GAADRD2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |