⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223747 | 0.72 | — | — | |
| SCHEMBL14930780 | 0.72 | — | — | |
| SCHEMBL14560503 | 0.72 | — | — | |
| SCHEMBL18077841 | 0.65 | — | — | |
| Iodoform SCHEMBL27906049 | 0.55 | — | — | |
| Iodoform SCHEMBL28065163 | 0.55 | — | — | |
| Iodoform SCHEMBL28140705 | 0.55 | — | — | |
| SCHEMBL1036689 | 0.55 | — | — | |
| SCHEMBL6800015 | 0.55 | — | — | |
| SCHEMBL96926 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359327-B2 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2016-06-07 | — | — | US | disclosed |
| US-9079882-B2 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-14 | — | — | US | disclosed |
| US-9079884-B2 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-14 | — | — | US | disclosed |
| US-9006432-B2 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-14 | — | — | US | disclosed |
| US-20140179924-A1 | Process for the preparation of cathepsin S inhibitors | JANSSEN PHARMACEUTICA NV (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140121374-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (US) | 2014-05-01 | — | — | US | disclosed |
| US-20140073795-A1 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140066624-A1 | Process for the preparation of substituted pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (US) | 2014-03-06 | — | — | US | disclosed |
| US-8647878-B2 | Highly refractive immersion liquids and their use | CARL ZEISS AG (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20130131401-A1 | PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS | JANSSEN PHARMACEUTICA, NV (BE) | 2013-05-23 | — | — | US | disclosed |
| US-20120309986-A1 | PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS | ANZALONE LUIGI (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120142928-A1 | PROCESS FOR THE PREPARATION OF CATHEPSIN S INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-06-07 | — | — | US | disclosed |
| US-20100212547-A1 | Highly Refractive Immersion Liquids And Their Use | CARL ZEISS AG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20080146759-A1 | Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material | IDEMITSU KOSAN CO., LTD (JP) | 2008-06-19 | — | — | US | disclosed |
| EP-0409466-B1 | Process for the preparation of a polyimide film | MITSUI TOATSU CHEMICALS (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5273998-A | Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5260407-A | Stretching, pyromellitic acid and 4,4'-bis(3-aminophenoxy) biphenyl | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5177216-A | DIASTEREOMERIC ESTER COMPOUND USEFUL AS AN INTERMEDIATE IN THE MAKING OF AN OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0456266-A1 | Method for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds, intermediates therefor and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |
| EP-0409466-A2 | Process for the preparation of a polyimide film | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-01-23 | — | — | EP | disclosed |