Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.74 |
| ▸ | HTR2C | P28335 | 5/20 | 0.74 |
| ▸ | HTR2A | P28223 | 5/20 | 0.74 |
| ▸ | DRD1 | P21728 | 4/20 | 0.74 |
| ▸ | HRH1 | P35367 | 4/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.74 |
| ▸ | DRD2 | P14416 | 2/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.74 |
| ▸ | HTR7 | P34969 | 5/20 | 0.62 |
| ▸ | HTR1D | P28221 | 4/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.62 |
| ▸ | HRH2 | P25021 | 3/20 | 0.62 |
| ▸ | HTR1B | P28222 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | HTR6 | P50406 | 3/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046365 | 1.00 | HTR2B (0.74) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL4227186 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL29356737 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL13701277 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL340674 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL30543449 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL675164 | 0.85 | HTR2B (1.00) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| SCHEMBL6057734 | 0.85 | HTR2B (0.84) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Volinanserin SCHEMBL29899671 | 0.84 | HTR2B (0.98) | HTR2BHTR2CHTR2ADRD1HRH1 | |
| Hydrochloric Acid SCHEMBL9650017 | 0.84 | HTR2B (0.82) | HTR2BHTR2CHTR2ADRD1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010143925-A | METHOD FOR PRODUCING (R)-α-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL | AVENTIS HOLDINGS INC | 2010-07-01 | — | — | JP | disclosed |
| WO-1999046245-A3 | PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL | HOECHST MARION ROUSSEL INC (US) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999046245-A2 | PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-16 | — | — | WO | disclosed |