Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 8/20 | 0.73 |
| ▸ | PIR | O00625 | 6/20 | 0.73 |
| ▸ | BRAF | P15056 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715824 | 1.00 | HSF1 (0.73) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621105 | 0.84 | HSF1 (1.00) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL30464304 | 0.83 | HSF1 (0.76) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL25715005 | 0.83 | HSF1 (0.76) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621292 | 0.81 | HSF1 (0.93) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL25715817 | 0.80 | HSF1 (0.50) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621116 | 0.80 | HSF1 (0.78) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621372 | 0.80 | HSF1 (0.84) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621471 | 0.79 | HSF1 (0.82) | HSF1PIRBRAFRAB9ANPC1 | |
| SCHEMBL16621489 | 0.79 | HSF1 (0.82) | HSF1PIRBRAFRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111005-A1 | CARBOXAMIDE SUBSTITUTED HETEROAROMATIC COMPOUNDS FOR TREATING CANCER | WMT AG (DE) | 2023-06-22 | — | — | WO | disclosed |