SCHEMBL30464985

SCHEMBL30464985

CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCN)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 4/20 0.58
▸ CCKBR P32239 6/20 0.56
▸ MC4R P32245 5/20 0.55
▸ KISS1R Q969F8 3/20 0.53
▸ CCKAR P32238 2/20 0.52
▸ CTSL P07711 1/20 0.51
▸ CTSH P09668 1/20 0.51
▸ CTSS P25774 1/20 0.51
▸ CTSK P43235 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464982 0.98 IL23R (0.59) IL23RCCKBRMC4RKISS1RCCKAR
SCHEMBL29814670 0.97 IL23R (0.61) IL23RCCKBRMC4RKISS1RCCKAR
SCHEMBL30464995 0.97 IL23R (0.61) IL23RCCKBRMC4RKISS1RCCKAR
SCHEMBL30464997 0.96 IL23R (0.57) IL23RCCKBRMC4RKISS1RCTSL
SCHEMBL30464993 0.94 IL23R (0.58) IL23RCCKBRMC4RKISS1RCTSL
SCHEMBL30465002 0.94 IL23R (0.60) IL23RMC4RCTSLCTSHCTSS
SCHEMBL30464981 0.94 IL23R (0.60) IL23RMC4RCTSLCTSHCTSS
SCHEMBL21146569 0.93 IL23R (0.66) IL23RMC4R
SCHEMBL30464987 0.92 IL23R (0.57) IL23RCCKBRMC4RKISS1RCCKAR
SCHEMBL19712194 0.91 MC4R (0.51) IL23RCCKBRMC4RKISS1RCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11622994-B2 Therapy for vitiligo CLINUVEL PHARMACEUTICALS LIMITED (AU) 2023-04-11 — — US claimed
EP-3573645-B1 ALPHA-MSH ANALOGUES USED IN THE TREATMENT OF XERODERMA PIGMENTOSUM VALLAURIX MC S A R L (MC) 2024-03-13 — — EP disclosed
EP-3030256-B1 NDP-MSH FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS CLINUVEL PHARMACEUTICALS LTD (AU) 2024-01-24 — — EP disclosed
US-11622994-B2 Therapy for vitiligo CLINUVEL PHARMACEUTICALS LIMITED (AU) 2023-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11622994-B2 Therapy for vitiligo MC1R, MC3R, MC5R IL23R 34/4885CCKBR 247/4885MC4R 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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