Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.70 |
| ▸ | BRAF | P15056 | 7/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14318406 | 0.89 | KIT (0.77) | KITBRAFEGFRABL1 | |
| SCHEMBL29562197 | 0.89 | KIT (0.77) | KITBRAFEGFRABL1 | |
| Hydrochloric Acid SCHEMBL29833672 | 0.88 | KIT (0.75) | KITBRAFEGFRABL1 | |
| SCHEMBL29562470 | 0.88 | BRAF (0.82) | KITBRAFFGFR1KDREGFR | |
| SCHEMBL6184307 | 0.88 | BRAF (0.82) | KITBRAFFGFR1KDREGFR | |
| SCHEMBL19500739 | 0.86 | KIT (0.78) | KITBRAFFGFR1EGFRABL1 | |
| SCHEMBL12871531 | 0.85 | KIT (0.84) | KITBRAFEGFRABL1 | |
| SCHEMBL24122650 | 0.84 | KIT (0.79) | KITBRAFFGFR1KDRSRC | |
| SCHEMBL30011074 | 0.84 | KIT (0.79) | KITBRAFFGFR1KDRSRC | |
| SCHEMBL21944007 | 0.83 | KIT (0.81) | KITBRAFEGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908899-A | FGFR4 inhibitor and preparation and application thereof | 重庆医科大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-115947693-B | FGFR4 inhibitor and preparation and application thereof | 重庆医科大学 | 2024-11-05 | — | — | CN | disclosed |
| CN-115947693-A | FGFR4 inhibitor and preparation and application thereof | 重庆医科大学 | 2023-04-11 | — | — | CN | disclosed |