Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.50 |
| ▸ | AKT2 | P31751 | 20/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 20/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21919545 | 1.00 | AKT1 (0.50) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| SCHEMBL22533529 | 1.00 | AKT1 (0.50) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| SCHEMBL3122777 | 1.00 | AKT1 (0.50) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| Hydrochloric Acid SCHEMBL3123973 | 0.99 | AKT1 (0.49) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| Hydrochloric Acid SCHEMBL191672 | 0.99 | AKT1 (0.49) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| Hydrochloric Acid SCHEMBL191587 | 0.99 | AKT1 (0.49) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| Trifluoroacetic Acid SCHEMBL192075 | 0.89 | AKT1 (0.53) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| SCHEMBL16488547 | 0.86 | AKT1 (0.52) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| SCHEMBL16488554 | 0.86 | AKT1 (0.52) | AKT1AKT2AKT3PIK3CAPRKG1 | |
| SCHEMBL16488551 | 0.86 | AKT1 (0.52) | AKT1AKT2AKT3PIK3CAPRKG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109540-A1 | HETEROCYCLIC COMPOUND WITH AKT KINASE INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |