Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 18/20 | 0.67 |
| ▸ | CDC7 | O00311 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | PRKACA | P17612 | 1/20 | 0.64 |
| ▸ | CDK7 | P50613 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.64 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.61 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.61 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241734 | 1.00 | PTK2 (0.67) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL31653644 | 0.91 | PTK2 (0.65) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL2051845 | 0.89 | PTK2 (0.62) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL2637548 | 0.89 | PTK2 (0.62) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL25692495 | 0.88 | PTK2 (0.68) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL31260481 | 0.87 | PTK2 (0.67) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL2038520 | 0.87 | PTK2 (0.61) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL2029802 | 0.86 | PTK2 (0.65) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL26123046 | 0.86 | PTK2 (0.65) | PTK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL2030366 | 0.85 | PTK2 (0.77) | PTK2CDC7ROCK2MAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109751-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVE AND MEDICINAL USE THEREOF | 希格生科（深圳）有限公司 | 2023-06-22 | — | — | WO | disclosed |