Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.46 |
| ▸ | DHFR | P00374 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252260 | 1.00 | PDE10A (0.46) | PDE10ADHFRLRRK2 | |
| SCHEMBL30467655 | 0.92 | PDE10A (0.38) | PDE10ADHFRLRRK2 | |
| SCHEMBL26771021 | 0.92 | PDE10A (0.45) | PDE10ADHFRLRRK2 | |
| SCHEMBL24252278 | 0.88 | PDE10A (0.40) | PDE10ADHFRLRRK2 | |
| Formic Acid SCHEMBL30467650 | 0.88 | PDE10A (0.35) | PDE10ADHFRLRRK2 | |
| SCHEMBL26773859 | 0.87 | KDR (0.39) | PDE10ADHFR | |
| SCHEMBL30451917 | 0.87 | PDE10A (0.42) | PDE10ADHFRLRRK2 | |
| SCHEMBL24252302 | 0.87 | PDE10A (0.42) | PDE10ADHFRLRRK2 | |
| SCHEMBL24252763 | 0.86 | PDE10A (0.35) | PDE10ADHFRLRRK2 | |
| SCHEMBL24252258 | 0.85 | PDE10A (0.34) | PDE10ADHFRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |