SCHEMBL30467959

SCHEMBL30467959

CN1CCC(Nc2ccc(S(=O)(=O)NC(=O)c3ccc(N4CCN(CC5=C(c6ccc(Cl)cc6)CC(C)(C)CC5)CC4)cc3Oc3ccc4[nH]ccc4c3)cc2[N+](=O)[O-])CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703407 1.00 BCL2 (1.00) BCL2
SCHEMBL1956893 0.97 BCL2 (0.94) BCL2
SCHEMBL2482022 0.97 BCL2 (0.94) BCL2
SCHEMBL1954919 0.96 BCL2 (0.92) BCL2
SCHEMBL1955278 0.95 BCL2 (0.91) BCL2
SCHEMBL1956083 0.95 BCL2 (0.91) BCL2
SCHEMBL1958050 0.95 BCL2 (0.91) BCL2
SCHEMBL1956817 0.95 BCL2 (0.93) BCL2
SCHEMBL1957606 0.95 BCL2 (0.90) BCL2
SCHEMBL1956094 0.95 BCL2 (0.90) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4218731-A2 MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT AbbVie Ireland Unlimited Company (IE) 2023-08-02 — — EP disclosed
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