SCHEMBL30467962

SCHEMBL30467962

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4cnc(O[C@@H]5CCN(C(CF)CF)C5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701436 1.00 BCL2 (1.00) BCL2
SCHEMBL1701874 0.93 BCL2 (1.00) BCL2
SCHEMBL30314148 0.93 BCL2 (1.00) BCL2
SCHEMBL1861473 0.92 BCL2 (1.00) BCL2
SCHEMBL30467957 0.92 BCL2 (1.00) BCL2
SCHEMBL1702329 0.92 BCL2 (1.00) BCL2
SCHEMBL1701435 0.91 BCL2 (1.00) BCL2
SCHEMBL30313987 0.91 BCL2 (1.00) BCL2
SCHEMBL1701646 0.90 BCL2 (1.00) BCL2
SCHEMBL30468040 0.90 BCL2 (1.00) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
EP-4218731-A2 MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT AbbVie Ireland Unlimited Company (IE) 2023-08-02 — — EP disclosed
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