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SCHEMBL30468093

SCHEMBL30468093

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4cnc(OCC5(F)CCOCC5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 1.00
▸ BCL2L1 Q07817 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700510 1.00 BCL2 (1.00) BCL2BCL2L1
SCHEMBL1700650 0.96 BCL2 (1.00) BCL2BCL2L1
SCHEMBL19419635 0.95 BCL2 (0.93) BCL2
SCHEMBL1701498 0.95 BCL2 (1.00) BCL2
SCHEMBL1701741 0.95 BCL2 (1.00) BCL2
SCHEMBL30313995 0.95 BCL2 (1.00) BCL2
SCHEMBL1701500 0.95 BCL2 (1.00) BCL2
SCHEMBL30313895 0.95 BCL2 (1.00) BCL2
SCHEMBL1701665 0.95 BCL2 (1.00) BCL2
SCHEMBL19424572 0.95 BCL2 (0.91) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
EP-4218731-A2 MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT AbbVie Ireland Unlimited Company (IE) 2023-08-02 — — EP disclosed
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