SCHEMBL30468232

SCHEMBL30468232

O=C(/C=C\c1ccccc1Cl)/C=C\c1ccccc1Cl

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.79
HDAC1 Q13547 1/20 0.67
HDAC8 Q9BY41 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
MAPT P10636 6/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
NFKB1 P19838 3/20 0.61
NFE2L2 Q16236 2/20 0.61
JUN P05412 1/20 0.61
MAOB P27338 3/20 0.61
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
HSP90AA1 P07900 1/20 0.61
HSD11B1 P28845 1/20 0.59
LMNA P02545 3/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2D6 P10635 2/20 0.57
CYP1A1 P04798 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744240 1.00 GSR (0.79) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL2744242 1.00 GSR (0.79) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL31553473 1.00 GSR (0.79) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL29428459 0.88 GSR (1.00) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL22596712 0.87 HDAC1 (0.67) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL11471846 0.85 GSR (0.65) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL1569438 0.85 HDAC1 (0.65) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL211297 0.85 HDAC1 (0.65) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL1569435 0.85 HDAC1 (0.65) GSRHDAC1HDAC8HDAC6MAPT
SCHEMBL322878 0.85 HDAC1 (0.65) GSRHDAC1HDAC8HDAC6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-219141974-U Self-checking belt scale 徐州上达科技有限公司 2023-06-06 CN disclosed