Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | WEE1 | P30291 | 9/20 | 0.44 |
| ▸ | AXL | P30530 | 8/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 8/20 | 0.44 |
| ▸ | MERTK | Q12866 | 8/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | PKMYT1 | Q99640 | 4/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29051773 | 0.99 | PTK2 (0.44) | PTK2WEE1AXLTYRO3MERTK | |
| Hydrochloric Acid SCHEMBL29051704 | 0.92 | CSF1R (0.45) | PTK2WEE1AXLTYRO3MERTK | |
| SCHEMBL30468504 | 0.91 | STK17A (0.45) | PTK2WEE1AXLTYRO3MERTK | |
| Hydrochloric Acid SCHEMBL29051920 | 0.90 | STK17A (0.44) | PTK2WEE1AXLTYRO3MERTK | |
| SCHEMBL30468400 | 0.88 | PTK2 (0.45) | PTK2WEE1AXLTYRO3MERTK | |
| Hydrochloric Acid SCHEMBL29051784 | 0.88 | PTK2 (0.44) | PTK2WEE1AXLTYRO3MERTK | |
| SCHEMBL30468428 | 0.86 | ACVR1 (0.42) | PTK2WEE1CAMK2D | |
| Hydrochloric Acid SCHEMBL29051869 | 0.85 | ACVR1 (0.42) | PTK2WEE1CAMK2D | |
| SCHEMBL29051707 | 0.83 | PTK2 (0.46) | PTK2WEE1AXLTYRO3MERTK | |
| Hydrochloric Acid SCHEMBL29051788 | 0.82 | BTK (0.45) | PTK2WEE1AXLTYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |