Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11955100 | 0.83 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL23240854 | 0.83 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL23240853 | 0.83 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL991393 | 0.82 | — | — | |
| SCHEMBL12747259 | 0.81 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL12747265 | 0.81 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL12747269 | 0.81 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL8077626 | 0.79 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL15953082 | 0.78 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL27833601 | 0.74 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029816-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-09 | — | — | US | disclosed |
| US-11364197-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-21 | — | — | US | disclosed |
| US-20210007971-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2021-01-14 | — | — | US | disclosed |
| US-10660850-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-05-26 | — | — | US | disclosed |
| US-20200069572-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2020-03-05 | — | — | US | disclosed |
| US-10434062-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-08 | — | — | US | disclosed |
| US-20190117557-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2019-04-25 | — | — | US | disclosed |
| US-10092512-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-09 | — | — | US | disclosed |
| EP-2252275-B1 | TEMPLATED OPEN FLOCS OF ANISOTROPIC PARTICLES FOR ENHANCED PULMONARY DELIVERY | UNIV TEXAS (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2727920-B1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-8841456-B2 | 1,5-naphthyridine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-05-22 | — | — | US | disclosed |
| EP-2727920-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2252275-A2 | TEMPLATED OPEN FLOCS OF ANISOTROPIC PARTICLES FOR ENHANCED PULMONARY DELIVERY | Board of Regents, The University of Texas System (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100221343-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-09-02 | — | — | US | disclosed |
| WO-2009103035-A2 | TEMPLATED OPEN FLOCS OF ANISOTROPIC PARTICLES FOR ENHANCED PULMONARY DELIVERY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090208582-A1 | Templated Open Flocs of Anisotropic Particles for Enhanced Pulmonary Delivery | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-08-20 | — | — | US | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | NRAS, RAF1, KRAS | CHRM2 3219/4885CHRM4 4515/4885CHRM5 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.