Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557908 | 1.00 | CNR1 (0.55) | CNR1EPHX2F2PLGPLAU | |
| SCHEMBL19707994 | 0.79 | EPHX2 (0.53) | EPHX2NPC1RAB9AEPHX1SMN1; SMN2 | |
| SCHEMBL30469272 | 0.78 | CNR1 (0.84) | CNR1NPC1MAPTRAB9ACYP2C9 | |
| SCHEMBL4117269 | 0.78 | CNR1 (0.84) | CNR1NPC1MAPTRAB9ACYP2C9 | |
| SCHEMBL21757192 | 0.77 | CNR1 (0.60) | CNR1EPHX2NPC1MAPTRAB9A | |
| SCHEMBL4117939 | 0.76 | CNR1 (0.64) | CNR1EPHX2NPC1MAPTRAB9A | |
| SCHEMBL4105980 | 0.76 | CNR1 (0.85) | CNR1NPC1MAPTRAB9ACYP2C9 | |
| SCHEMBL11175525 | 0.75 | F2 (0.54) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL21295553 | 0.75 | PDE4B (0.55) | EPHX2NPC1MAPTRAB9AEPHX1 | |
| SCHEMBL4106738 | 0.75 | NPC1 (0.64) | CNR1EPHX2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | claimed |
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |