SCHEMBL30469241

SCHEMBL30469241

COc1cccc(-c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 1.00
TP53 P04637 1/20 0.68
TSHR P16473 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20557353 1.00 CNR1 (1.00) CNR1TP53TSHR
SCHEMBL4117269 0.92 CNR1 (0.84) CNR1TP53TSHR
SCHEMBL30469272 0.92 CNR1 (0.84) CNR1TP53TSHR
SCHEMBL30469269 0.84 CNR1 (1.00) CNR1
SCHEMBL20557298 0.84 CNR1 (1.00) CNR1
SCHEMBL6197082 0.84 CNR1 (0.71) CNR1TP53TSHR
SCHEMBL20557858 0.83 CNR1 (1.00) CNR1
SCHEMBL30469248 0.83 CNR1 (1.00) CNR1
SCHEMBL22833983 0.82 CNR1 (1.00) CNR1
SCHEMBL29615095 0.82 CNR1 (1.00) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN claimed
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN disclosed