SCHEMBL30469267

SCHEMBL30469267

O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2ccncc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 18/20 1.00
CNR2 P34972 1/20 0.73
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20557649 1.00 CNR1 (1.00) CNR1CNR2MEN1KMT2A
SCHEMBL30469269 0.90 CNR1 (1.00) CNR1CNR2
SCHEMBL20557298 0.90 CNR1 (1.00) CNR1CNR2
SCHEMBL20557858 0.88 CNR1 (1.00) CNR1CNR2
SCHEMBL30469248 0.88 CNR1 (1.00) CNR1CNR2
SCHEMBL20557913 0.87 CNR1 (1.00) CNR1CNR2
SCHEMBL30469281 0.87 CNR1 (1.00) CNR1CNR2
SCHEMBL20557350 0.87 CNR1 (1.00) CNR1CNR2
SCHEMBL30469226 0.87 CNR1 (1.00) CNR1CNR2
SCHEMBL4922464 0.86 KMT2A (0.83) CNR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN claimed
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN disclosed