Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30470156 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL29326250 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL30469557 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24367761 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24367354 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24364045 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24364041 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24364042 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL30470639 | 1.00 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL24367387 | 0.99 | PRMT5 (0.47) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |