Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29081910 | 1.00 | HDAC6 (0.35) | HDAC6HTTNPC1GAAMAPK1 | |
| SCHEMBL24366820 | 1.00 | HDAC6 (0.35) | HDAC6HTTNPC1GAAMAPK1 | |
| SCHEMBL24367600 | 0.89 | HDAC6 (0.32) | HDAC6NPC1GAAMAPK1RAB9A | |
| SCHEMBL32689101 | 0.89 | HDAC6 (0.32) | HDAC6NPC1GAAMAPK1RAB9A | |
| SCHEMBL24366026 | 0.89 | HDAC6 (0.32) | HDAC6NPC1GAAMAPK1RAB9A | |
| SCHEMBL30471172 | 0.89 | HDAC6 (0.32) | HDAC6NPC1GAAMAPK1RAB9A | |
| SCHEMBL24364706 | 0.87 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL29081812 | 0.87 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL30470714 | 0.87 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL32689015 | 0.85 | HDAC6 (0.41) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |