⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688952 | 1.00 | — | — | |
| SCHEMBL24367507 | 1.00 | — | — | |
| SCHEMBL29335687 | 0.87 | PDE3B (0.34) | — | |
| SCHEMBL30469984 | 0.83 | — | — | |
| SCHEMBL29081431 | 0.83 | — | — | |
| SCHEMBL29347517 | 0.83 | — | — | |
| SCHEMBL29082045 | 0.81 | — | — | |
| SCHEMBL24366026 | 0.79 | HDAC6 (0.32) | — | |
| SCHEMBL32689101 | 0.79 | HDAC6 (0.32) | — | |
| SCHEMBL24367600 | 0.79 | HDAC6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |