Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674162 | 1.00 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL25390708 | 0.85 | HPGD (0.42) | PIK3CDPIK3CGPIK3CB | |
| SCHEMBL25393024 | 0.79 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL2675103 | 0.78 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL2674516 | 0.78 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL2109555 | 0.78 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL1114077 | 0.78 | PIK3CA (0.46) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL2273155 | 0.77 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL27833435 | 0.77 | PIM1 (0.38) | — | |
| SCHEMBL30670406 | 0.77 | SMN1; SMN2 (0.38) | PIK3CDPIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4694893-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME Therapeutics LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216229-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2024-10-17 | — | — | WO | disclosed |
| EP-4412617-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME Therapeutics LLC (US) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023058003-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2023-04-13 | — | — | WO | disclosed |