SCHEMBL30471854

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	8/20	0.45

▸	NPY5R	Q15761	7/20	0.45

▸	NPY1R	P25929	6/20	0.45

▸	TFPI	P10646	1/20	0.44

▸	NPBWR1	P48145	1/20	0.43

▸	NPY2R	P49146	4/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30880897	0.95	TFPI (0.49)	NPY4RNPY5RNPY1RTFPI
SCHEMBL30578724	0.92	TFPI (0.48)	NPY4RNPY5RNPY1RTFPI
SCHEMBL30880884	0.90	VIPR1 (0.46)	—
SCHEMBL30317546	0.89	TFPI (0.55)	TFPI
SCHEMBL30578726	0.88	TFPI (0.49)	NPY4RNPY5RNPY1RTFPI
SCHEMBL29523429	0.88	RXFP1 (0.52)	TFPI
SCHEMBL32670412	0.87	TFPI (0.45)	NPY4RNPY5RNPY1RTFPINPY2R
SCHEMBL31267170	0.86	NPY4R (0.53)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL29814926	0.85	TFPI (0.50)	TFPI
SCHEMBL30435760	0.85	TFPI (0.52)	NPY4RNPY5RNPY1RTFPINPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110105450-B	VEGF single domain antibody, nucleotide sequence and kit	深圳普瑞金生物药业股份有限公司	2023-07-04	—	—	CN	disclosed