Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989277 | 0.81 | MAPT (0.57) | MAPTAKR1B1BACE1NFKB1KMT2A | |
| SCHEMBL5015651 | 0.81 | MAPT (0.57) | MAPTAKR1B1BACE1NFKB1KMT2A | |
| SCHEMBL5015650 | 0.81 | MAPT (0.57) | MAPTAKR1B1BACE1NFKB1KMT2A | |
| SCHEMBL9550036 | 0.80 | BACE1 (0.77) | MAPTAKR1B1BACE1NFKB1CA1 | |
| SCHEMBL9658637 | 0.80 | MAPT (0.64) | MAPTAKR1B1BACE1NFKB1CA1 | |
| SCHEMBL9549936 | 0.80 | BACE1 (0.77) | MAPTAKR1B1BACE1NFKB1CA1 | |
| SCHEMBL9658649 | 0.80 | MAPT (0.64) | MAPTAKR1B1BACE1NFKB1CA1 | |
| SCHEMBL13524148 | 0.79 | MAPT (0.67) | MAPTBACE1NFKB1CA1CA2 | |
| SCHEMBL13056481 | 0.79 | MAPT (0.54) | MAPTAKR1B1BACE1NFKB1KMT2A | |
| SCHEMBL8022713 | 0.79 | EGFR (0.51) | MAPTAKR1B1BACE1SNCAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960020-A | Caffeic acid nitrone compound and preparation method and application thereof | 深圳枫语生物医药科技有限公司 | 2023-04-14 | — | — | CN | disclosed |