SCHEMBL30473142

SCHEMBL30473142

CON(C)C(=O)[C@H]1CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.35
KDM1A O60341 2/20 0.31
MAOB P27338 2/20 0.30
MAOA P21397 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473183 1.00 BTK (0.35) BTKKDM1AMAOBMAOAGAA
SCHEMBL30473133 0.85 BTK (0.39) BTKKDM1AMAOBMAOAGAA
SCHEMBL4479752 0.85 BTK (0.39) BTKKDM1AMAOBMAOAGAA
SCHEMBL4479750 0.85 BTK (0.39) BTKKDM1AMAOBMAOAGAA
SCHEMBL30473209 0.84 BTK (0.51) BTKKDM1AMAOBMAOAGAA
SCHEMBL30473159 0.79
SCHEMBL30473129 0.79
SCHEMBL30926206 0.79 BTK (0.38) BTKKDM1AMAOBMAOAGAA
SCHEMBL18588966 0.79 BTK (0.38) BTKKDM1AMAOBMAOAGAA
SCHEMBL30926268 0.79 BTK (0.38) BTKKDM1AMAOBMAOAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122772-A1 OXIME DERIVATIVES USEFUL AS T CELL ACTIVATORS GOSSAMER BIO SERVICES, INC. (US) 2023-06-29 WO disclosed