Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22367693 | 1.00 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL22367692 | 1.00 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL25216036 | 1.00 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL18205070 | 0.89 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL18205024 | 0.89 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL18009729 | 0.87 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL18026302 | 0.87 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL18205090 | 0.87 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL20475826 | 0.86 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL29705947 | 0.86 | PRMT5 (0.41) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542525-B | Selective inhibitors of protein arginine methyltransferase 5 (PRMT 5) | 普莱鲁德疗法有限公司 | 2023-06-27 | — | — | CN | disclosed |