Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211179 | 1.00 | HDAC1 (0.57) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL31108947 | 0.90 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL30474790 | 0.86 | HDAC1 (0.61) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL25221696 | 0.86 | HDAC1 (0.61) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL31109067 | 0.84 | HDAC1 (0.64) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL4581935 | 0.83 | HDAC1 (0.79) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL25244474 | 0.83 | HDAC2 (0.61) | HDAC1HDAC2HDAC3 | |
| SCHEMBL25219240 | 0.83 | HDAC2 (0.61) | HDAC1HDAC2HDAC3 | |
| SCHEMBL25216647 | 0.83 | HDAC2 (0.61) | HDAC1HDAC2HDAC3 | |
| SCHEMBL30474676 | 0.83 | HDAC2 (0.61) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4441033-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2023102162-A1 | TGONOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |