Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.45 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034765 | 1.00 | CRBN (0.45) | CRBNDDB1GSPT1POLB | |
| SCHEMBL24670689 | 0.87 | CRBN (0.44) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30883502 | 0.86 | CRBN (0.51) | CRBNDDB1GSPT1POLB | |
| SCHEMBL27225354 | 0.86 | CRBN (0.51) | CRBNDDB1GSPT1POLB | |
| SCHEMBL25935360 | 0.86 | CRBN (0.49) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30479043 | 0.86 | CRBN (0.49) | CRBNDDB1GSPT1POLB | |
| SCHEMBL25188803 | 0.84 | CRBN (0.47) | CRBNDDB1GSPT1POLB | |
| SCHEMBL25031349 | 0.83 | CRBN (0.46) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30475443 | 0.83 | CRBN (0.46) | CRBNDDB1GSPT1POLB | |
| SCHEMBL31727363 | 0.81 | CRBN (0.52) | CRBNDDB1GSPT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |