SCHEMBL30475702

SCHEMBL30475702

C=C(C)[C@@H]1CCC2=CCC[C@H](C)[C@]2(C)C1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.60
LMNA P02545 2/20 0.39
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 1/20 0.36
CYP1B1 Q16678 1/20 0.36
TSHR P16473 1/20 0.36
TRPA1 O75762 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP19A1 P11511 4/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30436640 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL567341 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL2513703 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL31091154 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL17513158 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL53289 1.00 CYP2C19 (0.60) CYP2C19LMNAALDH1A1ALOX15CYP1B1
Hydrogen Peroxide SCHEMBL335838 0.98 CYP2C19 (0.59) CYP2C19LMNAALDH1A1ALOX15CYP1B1
Alcohol SCHEMBL4998384 0.94 CYP2C19 (0.55) CYP2C19LMNAALDH1A1ALOX15CYP1B1
SCHEMBL13588481 0.84 CYP2C19 (0.44) CYP2C19ALDH1A1ALOX15CYP1B1CYP19A1
SCHEMBL4389152 0.84 CYP2C19 (0.44) CYP2C19ALDH1A1ALOX15CYP1B1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574718-B Use of SoSTPS2 as sesquiterpene synthases 中国中医科学院中药研究所 2024-04-16 CN claimed
CN-116790572-B Use of SoSTPS5 as a sesquiterpene synthase 中国中医科学院中药研究所 2024-04-09 CN disclosed
CN-116555238-B Use of SoSTPS1 as a sesquiterpene synthase 中国中医科学院中药研究所 2023-10-20 CN disclosed
CN-116790572-A Use of SoSTPS5 as a sesquiterpene synthase 中国中医科学院中药研究所 2023-09-22 CN disclosed
CN-116656659-A Use of SoSTPS4 as a sesquiterpene synthase 内蒙古民族大学 2023-08-29 CN disclosed
CN-116574718-A Use of SoSTPS2 as a sesquiterpene synthase 中国中医科学院中药研究所 2023-08-11 CN disclosed
CN-116555238-A Use of SoSTPS1 as a sesquiterpene synthase 中国中医科学院中药研究所 2023-08-08 CN disclosed
CN-116536295-A Use of SoSTPS3 as a sesquiterpene synthase 内蒙古民族大学 2023-08-04 CN disclosed