SCHEMBL30476643

SCHEMBL30476643

FC(F)Oc1ccc(I)cc1OCC1CC1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 16/20 0.56
PDE4B Q07343 14/20 0.56
PDE4A P27815 10/20 0.56
PDE4C Q08493 10/20 0.56
ABCB11 O95342 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23982177 1.00 PDE4D (0.56) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL8854690 0.82 PDE4D (0.60) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL6879083 0.82 PDE4B (0.60) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL1157286 0.82 PDE4B (0.56) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL131011 0.82 PDE4B (0.56) PDE4DPDE4BPDE4APDE4CABCB11
Hydrochloric Acid SCHEMBL31345245 0.81 PDE4B (0.55) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL28649051 0.80 PDE4B (0.37) PDE4DPDE4BPDE4APDE4C
SCHEMBL2954077 0.79 PDE4B (0.54) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL7475124 0.79 PDE4B (0.54) PDE4DPDE4BPDE4APDE4CABCB11
SCHEMBL23717240 0.79 PDE4B (0.60) PDE4DPDE4BPDE4APDE4CABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563244-B Substituted aza five-membered ring compound and application thereof in medicine 广东东阳光药业股份有限公司 2025-01-10 CN disclosed
CN-116354862-A Substituted azacyclic compounds and application thereof in medicines 广东东阳光药业有限公司 2023-06-30 CN disclosed