SCHEMBL30477202

SCHEMBL30477202

N#Cc1ccccc1-c1cc(-c2cccnc2)cn(-c2ccccc2)c1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.67
GRIA3 P42263 1/20 0.67
PDE4D Q08499 1/20 0.67
GLO1 Q04760 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
KDM4E B2RXH2 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP11B2 P19099 2/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B1 P15538 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
PTGS2 P35354 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
KDM5A P29375 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1881526 1.00 GRIA1 (0.67) GRIA1GRIA3PDE4DGLO1CNR1
SCHEMBL1879629 0.97 GRIA1 (0.62) GRIA1GRIA3PDE4DCNR1CNR2
SCHEMBL1887365 0.94 GRIA1 (0.65) GRIA1GRIA3PDE4DCNR1CNR2
SCHEMBL1889139 0.88 GRIA1 (0.67) GRIA1GRIA3PDE4DCNR1CNR2
SCHEMBL1885129 0.88 GRIA1 (0.72) GRIA1GRIA3PDE4DKDM4EGLA
SCHEMBL1890233 0.87 PDE4D (0.71) GRIA1GRIA3PDE4DKDM4EGLA
SCHEMBL30477203 0.87 PDE4D (0.71) GRIA1GRIA3PDE4DKDM4EGLA
SCHEMBL1887008 0.86 GRIA1 (0.67) GRIA1GRIA3PDE4DKDM4EGLA
SCHEMBL1879806 0.85 GRIA1 (0.66) GRIA1GRIA3PDE4DALDH1A1GABRG2
SCHEMBL1883356 0.85 GRIA1 (0.57) GRIA1GRIA3PDE4DCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116429937-A Detection method for related substances in pirenzepine bulk drug and application thereof 山东达因海洋生物制药股份有限公司 2023-07-14 CN claimed