SCHEMBL30477207

SCHEMBL30477207

O=C(O)c1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccc2)c1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.67
GRIA3 P42263 1/20 0.67
PDE4D Q08499 1/20 0.67
KDM4E B2RXH2 4/20 0.43
DHODH Q02127 2/20 0.43
GRM5 P41594 3/20 0.40
MAPK1 P28482 1/20 0.40
KDM4C Q9H3R0 2/20 0.38
KDM6B O15054 1/20 0.38
KDM4A O75164 1/20 0.38
KDM5C P41229 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
KDM3A Q9Y4C1 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30477208 0.91 GRIA1 (0.64) GRIA1GRIA3PDE4DKDM4EDHODH
SCHEMBL1892150 0.91 GRIA1 (0.64) GRIA1GRIA3PDE4DKDM4EDHODH
SCHEMBL1886198 0.91 GRIA1 (0.64) GRIA1GRIA3PDE4DKDM4EDHODH
SCHEMBL1893233 0.88 GRIA1 (0.61) GRIA1GRIA3PDE4DKDM4EGRM5
SCHEMBL1885448 0.88 GRIA1 (0.61) GRIA1GRIA3PDE4DKDM4EGRM5
SCHEMBL1884216 0.85 GRIA1 (0.69) GRIA1GRIA3PDE4DGRM5MAPK1
SCHEMBL1887704 0.85 GRIA1 (0.71) GRIA1GRIA3PDE4DKDM4EGRM5
SCHEMBL1884948 0.83 GRIA1 (0.70) GRIA1GRIA3PDE4DGRM5
SCHEMBL1883158 0.83 GRIA1 (0.69) GRIA1GRIA3PDE4DKDM4EGRM5
SCHEMBL1884312 0.83 GRIA1 (0.69) GRIA1GRIA3PDE4DDHODHGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116429937-A Detection method for related substances in pirenzepine bulk drug and application thereof 山东达因海洋生物制药股份有限公司 2023-07-14 CN claimed