Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.69 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | GRM5 | P41594 | 13/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885494 | 1.00 | GRIA1 (0.69) | GRIA1GRIA3PDE4DGRM5KDM4E | |
| SCHEMBL1887019 | 0.89 | GRIA1 (0.72) | GRIA1GRIA3PDE4DGRM5KDM4E | |
| SCHEMBL1884948 | 0.86 | GRIA1 (0.70) | GRIA1GRIA3PDE4DGRM5MAPT | |
| SCHEMBL1884881 | 0.84 | GRIA1 (0.82) | GRIA1GRIA3PDE4DGRM5KDM4E | |
| SCHEMBL1890140 | 0.83 | GRIA1 (0.67) | GRIA1GRIA3PDE4DGRM5 | |
| SCHEMBL1885398 | 0.83 | GRIA1 (0.60) | GRIA1GRIA3PDE4DGRM5TSHR | |
| SCHEMBL1884361 | 0.83 | GRIA1 (0.60) | GRIA1GRIA3PDE4DGRM5KDM4E | |
| SCHEMBL1884288 | 0.83 | GRIA1 (0.60) | GRIA1GRIA3PDE4DGRM5 | |
| SCHEMBL1889782 | 0.83 | GRIA1 (0.60) | GRIA1GRIA3PDE4DGRM5MAPT | |
| SCHEMBL1880087 | 0.82 | GRIA1 (0.69) | GRIA1GRIA3PDE4DGRM5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116429937-A | Detection method for related substances in pirenzepine bulk drug and application thereof | 山东达因海洋生物制药股份有限公司 | 2023-07-14 | — | — | CN | claimed |