Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477359 | 0.89 | FOLH1 (0.58) | FOLH1HRH4MMEACECPA1 | |
| SCHEMBL29533784 | 0.86 | FOLH1 (0.52) | FOLH1HRH4MMEACECPA1 | |
| SCHEMBL30477360 | 0.82 | FOLH1 (0.51) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL4599154 | 0.80 | FOLH1 (0.51) | FOLH1HRH4MMEACECPA1 | |
| SCHEMBL4599159 | 0.80 | FOLH1 (0.51) | FOLH1HRH4MMEACECPA1 | |
| SCHEMBL31510462 | 0.79 | MME (0.57) | FOLH1HRH4MMEACECPA1 | |
| SCHEMBL31720502 | 0.79 | ERAP2 (0.73) | ACEMMP9MMP8MMP2ERAP2 | |
| SCHEMBL29892410 | 0.78 | NAALAD2 (0.67) | FOLH1NAALAD2HPGD | |
| SCHEMBL29350328 | 0.78 | ERAP2 (0.65) | ACEERAP2 | |
| SCHEMBL7857962 | 0.78 | HRH4 (0.51) | HRH4MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540161-B2 | Linkers | BICYCLETX LIMITED (GB) | 2026-02-03 | — | — | US | disclosed |
| CN-116348476-A | Peptide-based linkers | 拜斯科技术开发有限公司 | 2023-06-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540161-B2 | Linkers | ADM2, CDA, DCTD | FOLH1 26/4885HRH4 391/4885MME 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.